Tools for physiology labs: inexpensive equipment for physiological stimulation.

We describe the design of inexpensive equipment and software for physiological stimulation in the neurobiology teaching laboratory. The core component is a stimulus isolation unit (SIU) that uses DC-DC converters, rather than expensive high-voltage batteries, to generate isolated power at high voltage.

The SIU has no offset when inactive and produces pulses up to 100 V with moderately fast (50 μs) rise times. We also describe two methods of stimulus timing control. The first is a simplified conventional, stand-alone analog pulse generator. The second uses a digital microcontroller interfaced with a personal computer.

The SIU has performed well and withstood intensive use in our undergraduate physiology laboratory. This project is part of our ongoing effort to make reliable low-cost physiology equipment available for both student teaching and faculty research laboratories.

From research lab to standard environmental analysis tool: Will NASBA make the leap?

 

Nucleic acid sequence-based amplification (NASBA) is a sensitive and efficient molecular tool for amplification of RNA and has been widely adopted in clinical diagnostics. Monitoring of water and other environmental samples demands sensitive techniques, as potential pathogens may be in low concentrations and require only a few infectious units to infect their host.

ZIP

E1KP1083 1mgPHYSICAL AND CHEMICAL PROPERTIES
EUR 526.8

ZIP

TP1924-10mg 10mg Ask for price
Description: ZIP

ZIP

TP1924-1g 1g Ask for price
Description: ZIP

ZIP

TP1924-1mg 1mg Ask for price
Description: ZIP

ZIP

TP1924-50mg 50mg Ask for price
Description: ZIP

ZIP

TP1924-5mg 5mg Ask for price
Description: ZIP

ZIP Kinase Antibody

DF7863 100ul
EUR 280
Description: Human,Mouse,Rat

ZIP Kinase Antibody

DF7863-100ul 100ul
EUR 280

ZIP Kinase Antibody

DF7863-200ul 200ul
EUR 350

anti-ZIP Kinase

YF-PA23562 50 ul
EUR 400.8
Description: Mouse polyclonal to ZIP Kinase

ZIP (SCRAMBLED)

A8830-1 1 mg
EUR 188.4
Description: IC50: By suppressing protein kinase M? (PKM?), ZIP reverses late-phase LTP with an IC50 of 1 - 2.5 ?M.Long-term potentiation (LTP), a persistent synaptic enhancement, is considered to be a substrate for memory.

ZIP, Biotinylated

B5407-1 1 mg
EUR 583.2

ZIP, Biotinylated

TP2303-10mg 10mg Ask for price
Description: ZIP, Biotinylated

ZIP, Biotinylated

TP2303-1g 1g Ask for price
Description: ZIP, Biotinylated

ZIP, Biotinylated

TP2303-1mg 1mg Ask for price
Description: ZIP, Biotinylated

ZIP, Biotinylated

TP2303-50mg 50mg Ask for price
Description: ZIP, Biotinylated

ZIP, Biotinylated

TP2303-5mg 5mg Ask for price
Description: ZIP, Biotinylated

Rat ZIP zinc transporter 14 (ZIP-14) ELISA Kit

QY-E11716 96T
EUR 448.8

Anti-ZIP kinase antibody

PAab09640 100 ug
EUR 494.4

Anti-ZIP Kinase Antibody

STJ500732 100 µg
EUR 571.2

ZIP (SCRAMBLED) Acetate

T22175L-10mg 10mg Ask for price
Description: ZIP (SCRAMBLED) Acetate

ZIP (SCRAMBLED) Acetate

T22175L-1g 1g Ask for price
Description: ZIP (SCRAMBLED) Acetate

ZIP (SCRAMBLED) Acetate

T22175L-1mg 1mg Ask for price
Description: ZIP (SCRAMBLED) Acetate

ZIP (SCRAMBLED) Acetate

T22175L-50mg 50mg Ask for price
Description: ZIP (SCRAMBLED) Acetate

ZIP (SCRAMBLED) Acetate

T22175L-5mg 5mg Ask for price
Description: ZIP (SCRAMBLED) Acetate

Anti-ZIP Kinase Antibody FITC

STJ500734 100 µg
EUR 703.2

Anti-ZIP Kinase Antibody BIOTIN

STJ500733 100 µg
EUR 703.2

Rabbit Anti Human Zip Kinase (Aa279-298) Polyclonal Antibody

CPBT-66377RH 0.1 mg
EUR 696

Polyclonal DAPK3 / ZIP Kinase Antibody (Internal)

APR02264G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human DAPK3 / ZIP Kinase (Internal). This antibody is tested and proven to work in the following applications:

ZIP Kinase (DAPK3) rabbit polyclonal antibody, Purified

SP1242P 100 µg Ask for price

4440Lab Coat+Zip White Size M

SAF0258 PK50
EUR 634.52

4440Lab Coat+Zip White Size S

SAF0259 PK50
EUR 608.41

4440Lab Coat+Zip White Size XL

SAF0260 PK50
EUR 634.52

4440Lab Coat+Zip White Size XXL

SAF0254 PK50
EUR 470.02

Myr-ZIP

T35535-10mg 10mg Ask for price
Description: Myr-ZIP

Myr-ZIP

T35535-1g 1g Ask for price
Description: Myr-ZIP

Myr-ZIP

T35535-1mg 1mg Ask for price
Description: Myr-ZIP

Myr-ZIP

T35535-50mg 50mg Ask for price
Description: Myr-ZIP

Myr-ZIP

T35535-5mg 5mg Ask for price
Description: Myr-ZIP

ZIP Kinase (DAPK3) rabbit polyclonal antibody, Aff - Purified

AP07741PU-N 50 µg Ask for price

ZIP Kinase (DAPK3) rabbit polyclonal antibody, Aff - Purified

AP21094PU-N 100 µg Ask for price

4400 Lab Coat+Zip White Size L

SAF0245 PK50
EUR 332.93

4400 Lab Coat+Zip White Size M

SAF0246 PK50
EUR 338.15

4400 Lab Coat+Zip White Size S

SAF0247 PK50
EUR 359.04

4400 Lab Coat+Zip White Size XL

SAF0248 PK50
EUR 338.15

ZIP acetate(863987-12-6 free base)

TP1924L1-10mg 10mg Ask for price
Description: ZIP acetate(863987-12-6 free base)

ZIP acetate(863987-12-6 free base)

TP1924L1-1g 1g Ask for price
Description: ZIP acetate(863987-12-6 free base)

ZIP acetate(863987-12-6 free base)

TP1924L1-1mg 1mg Ask for price
Description: ZIP acetate(863987-12-6 free base)

ZIP acetate(863987-12-6 free base)

TP1924L1-50mg 50mg Ask for price
Description: ZIP acetate(863987-12-6 free base)

ZIP acetate(863987-12-6 free base)

TP1924L1-5mg 5mg Ask for price
Description: ZIP acetate(863987-12-6 free base)

4400 Lab Coat+Zip White Size XXL

SAF0242 PK50
EUR 338.15

4400 Lab Coat+Zip White Size 4XL

SAF0244 PK50
EUR 353.82

Tyvek Lab Coat Mandarin Collar Zip Large

SAF95540 PK25
EUR 953.04

Tyvek Lab Coat Mandarin Collar Zip Medium

SAF95560 PK25
EUR 953.04

Spz1 (GFP-tagged) - Mouse spermatogenic Zip 1 (Spz1)

MG205903 10 µg Ask for price

Rabbit Anti-Human solute carrier family 39 (zinc transporter), member 4 (Zip 4) IgG (aff pure)

AB-23235-A 100ug
EUR 578.4

Rabbit Anti-Human solute carrier family 39 (zinc transporter), member 4 (Zip 4) IgG (aff pure)

AB-23259-A 100ug
EUR 578.4

Tensioning Tool for 18 to 175 Pound Cable/Zip Ties Polycarbonate

SI-06830-07 EA
EUR 91.2

Sample Bag Self-seal LDPE Double Zip-lock 102 X 152mm X500

DD29829 PK500
EUR 320.4

Human solute carrier family 39 (zinc transporter), member 4 (Zip 4) Control/blocking peptide

AB-23235-P 100ug
EUR 196.8

Human solute carrier family 39 (zinc transporter), member 4 (Zip 4)Control/blocking peptide

AB-23259-P 100 ug
EUR 196.8

anti- ZIP4 antibody

FNab09641 100µg
EUR 702
Description: Antibody raised against ZIP4

anti- ZIP7 antibody

FNab09642 100µg
EUR 658.5
Description: Antibody raised against ZIP7

anti- ZIP8 antibody

FNab09643 100µg
EUR 658.5
Description: Antibody raised against ZIP8

Anti-SLC39A7/Zip7 Antibody

A07719 100ul
EUR 476.4
Description: Rabbit Polyclonal SLC39A7/Zip7 Antibody. Validated in WB and tested in Human, Mouse.

Anti-SLC39A2/Zip2 Antibody

A09140 100ul
EUR 476.4
Description: Rabbit Polyclonal SLC39A2/Zip2 Antibody. Validated in WB and tested in Human.

Anti-SLC39A9/Zip9 Antibody

A13097 100ul
EUR 476.4
Description: Rabbit Polyclonal SLC39A9/Zip9 Antibody. Validated in WB and tested in Human.

anti- ZIPK-Phospho 311Ser antibody

FNab09644 100µg
EUR 658.5
Description: Antibody raised against ZIPK-Phospho 311Ser

Rabbit Anti-Human Zinc Transporter 1 (ZIP1) IgG #1 (aff pure)

ZIP11-A 100 ug
EUR 578.4

Rabbit Anti-Mouse Zinc Transporter 2 (ZIP2) IgG #1 (aff pure)

ZIP21-A 100 ug
EUR 578.4

Rabbit Anti-Human Zinc Transporter 2 (ZIP2) IgG #1 (aff pure)

ZIP22-A 100 ug
EUR 578.4

Rabbit Anti-Mouse Zinc Transporter 3 (ZIP3) IgG #1 (aff pure)

ZIP31-A 100 ug
EUR 578.4

Rabbit Anti-Mouse Zinc Transporter 4 (ZIP4) IgG #1 (aff pure)

ZIP41-A 100 ug
EUR 578.4

Rabbit Anti-Human Zinc Transporter 4 (ZIP4) IgG #1 (aff pure)

ZIP42-A 100 ug
EUR 578.4

Rabbit Anti-Mouse Zinc Transporter 5 (ZIP5) IgG #1 (aff pure)

ZIP51-A 100 ug
EUR 578.4

Rabbit Anti-Mouse Zinc Transporter 6 (ZIP6) IgG #1 (aff pure)

ZIP61-A 100 ug
EUR 578.4

Rabbit Anti-Human Zinc Transporter 6 (ZIP6) IgG #1 (aff pure)

ZIP62-A 100 ug
EUR 578.4

Rabbit Anti-Human Zinc Transporter 7 (ZIP7) IgG #1 (aff pure)

ZIP71-A 100 ug
EUR 578.4

LSR (untagged)-Human liver-specific bHLH-Zip transcription factor (cDNA clone MGC:10659 IMAGE:3641235), complete cds

SC123763 10 µg Ask for price

ZIP10 Antibody

24824-100ul 100ul
EUR 468

ZIP11 Antibody

24829-100ul 100ul
EUR 468

ZIP10 Antibody

25233-100ul 100ul
EUR 468

ZIP12 Antibody

25234-100ul 100ul
EUR 468

ZIP13 Antibody

25235-100ul 100ul
EUR 468

ZIP14 Antibody

25236-100ul 100ul
EUR 468

ZIP12 Antibody

6101-002mg 0.02 mg
EUR 206.18
Description: ZIP12 Antibody: The zinc transporter ZIP12, also known as SLC39A12, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP12 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Increased levels of ZIP12 have been observed during acute inflammation in the airway and asthma, suggesting that it may be promote increased zinc uptake, as this can reduce inflammation. The zinc content in brains in individuals with schizophrenia is lower than in individuals with other cerebral diseases, and mutations in ZIP12 have been observed in a small group of schizophrenic patients, suggesting that ZIP12 may play a role in this disease.

ZIP12 Antibody

6101-01mg 0.1 mg
EUR 523.7
Description: ZIP12 Antibody: The zinc transporter ZIP12, also known as SLC39A12, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP12 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Increased levels of ZIP12 have been observed during acute inflammation in the airway and asthma, suggesting that it may be promote increased zinc uptake, as this can reduce inflammation. The zinc content in brains in individuals with schizophrenia is lower than in individuals with other cerebral diseases, and mutations in ZIP12 have been observed in a small group of schizophrenic patients, suggesting that ZIP12 may play a role in this disease.

ZIP13 Antibody

6103-002mg 0.02 mg
EUR 206.18
Description: ZIP13 Antibody: The zinc transporter ZIP13, also known as SLC39A13, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP13 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Mutations in ZIP13 have recently been shown to cause a spondylocheiro dysplastic form of Ehlers-Danlos syndrome (SCD-EDS), a generalized skeletal dysplasia involving mainly the spine with clinical abnormalities of the hands in addition to EDS-like features. Other experiments have shown that ZIP13 is required for proper connective tissue development and is involved in BMP/TGF- signaling pathways.

ZIP13 Antibody

6103-01mg 0.1 mg
EUR 523.7
Description: ZIP13 Antibody: The zinc transporter ZIP13, also known as SLC39A13, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP13 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Mutations in ZIP13 have recently been shown to cause a spondylocheiro dysplastic form of Ehlers-Danlos syndrome (SCD-EDS), a generalized skeletal dysplasia involving mainly the spine with clinical abnormalities of the hands in addition to EDS-like features. Other experiments have shown that ZIP13 is required for proper connective tissue development and is involved in BMP/TGF- signaling pathways.

ZIP14 Antibody

6105-002mg 0.02 mg
EUR 206.18
Description: ZIP14 Antibody: The zinc transporter ZIP14, also known as SLC39A14, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP14 is a glycosylated multipass plasma membrane protein that belongs to the ZIP transporter subfamily LIV-1. ZIP14 has been shown to contribute to the hypozincemia of inflammation and infection and is regulated in the liver by IL-6. In addition to zinc, ZIP14 is also involved in the cellular uptake of non-transferrin-bound iron as well as iron bound to transferrin.

ZIP14 Antibody

6105-01mg 0.1 mg
EUR 523.7
Description: ZIP14 Antibody: The zinc transporter ZIP14, also known as SLC39A14, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP14 is a glycosylated multipass plasma membrane protein that belongs to the ZIP transporter subfamily LIV-1. ZIP14 has been shown to contribute to the hypozincemia of inflammation and infection and is regulated in the liver by IL-6. In addition to zinc, ZIP14 is also involved in the cellular uptake of non-transferrin-bound iron as well as iron bound to transferrin.

ZIP10 Antibody

6099-002mg 0.02 mg
EUR 206.18
Description: ZIP10 Antibody: ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies.

ZIP10 Antibody

6099-01mg 0.1 mg
EUR 523.7
Description: ZIP10 Antibody: ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies.

ZIP11 Antibody

5001-002mg 0.02 mg
EUR 206.18
Description: ZIP11 Antibody: ZIP11, also known as Slc39A11, is a member of the broader ZIP family of multi-transmembrane domain metal ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Members of the ZIP family generally transport metal ions from the cell exterior or lumen of intracellular organelles into the cytoplasm, as opposed to the ZnT (SLC30) family of zinc transporters that serve to reduce intracellular zinc availability by promoting zinc efflux from cells or into intracellular vesicles. At least three isoforms of ZIP11 are known to exist.

ZIP11 Antibody

5001-01mg 0.1 mg
EUR 523.7
Description: ZIP11 Antibody: ZIP11, also known as Slc39A11, is a member of the broader ZIP family of multi-transmembrane domain metal ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Members of the ZIP family generally transport metal ions from the cell exterior or lumen of intracellular organelles into the cytoplasm, as opposed to the ZnT (SLC30) family of zinc transporters that serve to reduce intracellular zinc availability by promoting zinc efflux from cells or into intracellular vesicles. At least three isoforms of ZIP11 are known to exist.

ZIP10 Antibody

4991-002mg 0.02 mg
EUR 206.18
Description: ZIP10 Antibody: ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies. At least three isoforms of ZIP10 are known to exist.

ZIP10 Antibody

4991-01mg 0.1 mg
EUR 523.7
Description: ZIP10 Antibody: ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies. At least three isoforms of ZIP10 are known to exist.

Zinc Transporter ZIP4 (ZIP4) Antibody

abx239641-100ug 100 ug
EUR 661.2

Zinc Transporter ZIP7 (ZIP7) Antibody

abx239642-100ug 100 ug
EUR 610.8

Zinc Transporter ZIP8 (ZIP8) Antibody

abx239643-100ug 100 ug
EUR 610.8

Zinc Transporter ZIP2 (ZIP2) Antibody

abx218628-100ug 100 ug
EUR 526.8

Zinc Transporter ZIP9 (ZIP9) Antibody

20-abx008112
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Zinc Transporter ZIP7 (ZIP7) Antibody

20-abx008550
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Polyclonal ZIP10 Antibody

APR10786G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ZIP10 . This antibody is tested and proven to work in the following applications:

Polyclonal ZIP10 Antibody

APR10787G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ZIP10 . This antibody is tested and proven to work in the following applications:

Polyclonal ZIP11 Antibody

APR10788G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ZIP11 . This antibody is tested and proven to work in the following applications:

Polyclonal ZIP12 Antibody

APR10789G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ZIP12 . This antibody is tested and proven to work in the following applications:

Polyclonal ZIP13 Antibody

APR10790G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ZIP13 . This antibody is tested and proven to work in the following applications:

Polyclonal ZIP14 Antibody

APR10791G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ZIP14 . This antibody is tested and proven to work in the following applications:

Zip12 Polyclonal Antibody

29534-100ul 100ul
EUR 302.4

Zip12 Polyclonal Antibody

29534-50ul 50ul
EUR 224.4

Zip12 Polyclonal Antibody

E916006 100ul
EUR 225
Description: Available in various conjugation types.

ZIP1 Antibody

25224-100ul 100ul
EUR 468

ZIP2 Antibody

25225-100ul 100ul
EUR 468

ZIP3 Antibody

25226-100ul 100ul
EUR 468

ZIP5 Antibody

25228-100ul 100ul
EUR 468

ZIP6 Antibody

25229-100ul 100ul
EUR 468

ZIP7 Antibody

25230-100ul 100ul
EUR 468

ZIP8 Antibody

25231-100ul 100ul
EUR 468

ZIP9 Antibody

25232-100ul 100ul
EUR 468

ZIP1 Antibody

6081-002mg 0.02 mg
EUR 206.18
Description: ZIP1 Antibody: ZIP1, also known as ZIRTL (zinc-iron regulated transporter-like), is the first mammalian member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP1 expression is markedly downregulated in a number of cancerous tissues and is thought to function as a tumor suppressor gene in prostate cancer. More recent studies have shown that overexpression of ZIP1 and concomitant increased levels of intracellular zinc in PC-3 cells cause a significant inhibition of NF-κB, leading to down-regulation of the antiapoptotic protein Bcl-2, Bcl-XL, and the apoptosis inhibitor XIAP, reducing the malignant potential of prostate cancer cells in vitro and in vivo.

ZIP1 Antibody

6081-01mg 0.1 mg
EUR 523.7
Description: ZIP1 Antibody: ZIP1, also known as ZIRTL (zinc-iron regulated transporter-like), is the first mammalian member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP1 expression is markedly downregulated in a number of cancerous tissues and is thought to function as a tumor suppressor gene in prostate cancer. More recent studies have shown that overexpression of ZIP1 and concomitant increased levels of intracellular zinc in PC-3 cells cause a significant inhibition of NF-κB, leading to down-regulation of the antiapoptotic protein Bcl-2, Bcl-XL, and the apoptosis inhibitor XIAP, reducing the malignant potential of prostate cancer cells in vitro and in vivo.

ZIP2 Antibody

6083-002mg 0.02 mg
EUR 206.18
Description: ZIP2 Antibody: The zinc transporter ZIP2, also known as SLC39A2, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP3, ZIP2-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.

ZIP2 Antibody

6083-01mg 0.1 mg
EUR 523.7
Description: ZIP2 Antibody: The zinc transporter ZIP2, also known as SLC39A2, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP3, ZIP2-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.

ZIP3 Antibody

6085-002mg 0.02 mg
EUR 206.18
Description: ZIP3 Antibody: The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP2, ZIP3-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.

ZIP3 Antibody

6085-01mg 0.1 mg
EUR 523.7
Description: ZIP3 Antibody: The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP2, ZIP3-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.

ZIP5 Antibody

6089-002mg 0.02 mg
EUR 206.18
Description: ZIP5 Antibody: The zinc transporter ZIP5, also known as SLC39A5, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP5 is closely related to ZIP4, and is found in many of the same tissues, including intestine, pancreas, liver, and kidney, but unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and its activity is not downregulated by zinc repletion. Recent evidence suggests that ZIP4 and ZIP5 are reciprocally regulated, with translation of ZIP5 mRNA decreasing and ZIP5 protein being rapidly internalized and degraded in response to zinc deficiency.

ZIP5 Antibody

6089-01mg 0.1 mg
EUR 523.7
Description: ZIP5 Antibody: The zinc transporter ZIP5, also known as SLC39A5, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP5 is closely related to ZIP4, and is found in many of the same tissues, including intestine, pancreas, liver, and kidney, but unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and its activity is not downregulated by zinc repletion. Recent evidence suggests that ZIP4 and ZIP5 are reciprocally regulated, with translation of ZIP5 mRNA decreasing and ZIP5 protein being rapidly internalized and degraded in response to zinc deficiency.

ZIP6 Antibody

6091-002mg 0.02 mg
EUR 206.18
Description: ZIP6 Antibody: The zinc transporter ZIP6, also known as SLC39A6, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP6 expression has also been reported in human cervical cancer and the HeLa cell line; down-regulation of ZIP6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP6 plays a regulatory role on the ERK1/2-Snail/Slug pathway.

ZIP6 Antibody

6091-01mg 0.1 mg
EUR 523.7
Description: ZIP6 Antibody: The zinc transporter ZIP6, also known as SLC39A6, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP6 expression has also been reported in human cervical cancer and the HeLa cell line; down-regulation of ZIP6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP6 plays a regulatory role on the ERK1/2-Snail/Slug pathway.

ZIP7 Antibody

6093-002mg 0.02 mg
EUR 206.18
Description: ZIP7 Antibody: The zinc transporter ZIP7, also known as SLC39A7, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP7 was initially identified while characterizing genes in the major histocompatibility complex on chromosome 17. ZIP7 mRNA is abundantly and widely expressed and the protein localizes to the Golgi apparatus. It functions to transport intracellular zinc from the Golgi apparatus to the cytoplasm of the cell. ZIP7 expression is expressed by zinc. ZIP7 has been suggested to act a hub for tyrosine kinase activation and may thus be a potential therapeutic target for diseases such as cancer where prevention of tyrosine kinase activation would be advantageous.

ZIP7 Antibody

6093-01mg 0.1 mg
EUR 523.7
Description: ZIP7 Antibody: The zinc transporter ZIP7, also known as SLC39A7, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP7 was initially identified while characterizing genes in the major histocompatibility complex on chromosome 17. ZIP7 mRNA is abundantly and widely expressed and the protein localizes to the Golgi apparatus. It functions to transport intracellular zinc from the Golgi apparatus to the cytoplasm of the cell. ZIP7 expression is expressed by zinc. ZIP7 has been suggested to act a hub for tyrosine kinase activation and may thus be a potential therapeutic target for diseases such as cancer where prevention of tyrosine kinase activation would be advantageous.

ZIP8 Antibody

6095-002mg 0.02 mg
EUR 206.18
Description: ZIP8 Antibody: The zinc transporter ZIP8, also known as SLC39A9, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP8 is glycosylated and located at the plasma membrane and mitochondria. It has been identified as the transporter responsible for transport of the toxic Cadmium cation. ZIP8 has also been suggested to play a role in the regulation of interferon-gamma expression in activated human T cells.

ZIP8 Antibody

6095-01mg 0.1 mg
EUR 523.7
Description: ZIP8 Antibody: The zinc transporter ZIP8, also known as SLC39A9, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP8 is glycosylated and located at the plasma membrane and mitochondria. It has been identified as the transporter responsible for transport of the toxic Cadmium cation. ZIP8 has also been suggested to play a role in the regulation of interferon-gamma expression in activated human T cells.

ZIP9 Antibody

6097-002mg 0.02 mg
EUR 206.18
Description: ZIP9 Antibody: The zinc transporter ZIP9, also known as SLC39A9, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP9 is a multipass membrane protein that belongs to the ZIP transporter subfamily I. It is located at the trans-Golgi network regardless of zinc presence and is thought to be a zinc homeostasis regulator acting in the secretory pathway without significantly altering cytosolic zinc homeostasis.

ZIP9 Antibody

6097-01mg 0.1 mg
EUR 523.7
Description: ZIP9 Antibody: The zinc transporter ZIP9, also known as SLC39A9, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP9 is a multipass membrane protein that belongs to the ZIP transporter subfamily I. It is located at the trans-Golgi network regardless of zinc presence and is thought to be a zinc homeostasis regulator acting in the secretory pathway without significantly altering cytosolic zinc homeostasis.

ZIP9 antibody

70R-51026 100 ul
EUR 292.8
Description: Purified Polyclonal ZIP9 antibody

ZIP7 antibody

70R-50575 100 ul
EUR 292.8
Description: Purified Polyclonal ZIP7 antibody

ZIP1 Antibody

47986-100ul 100ul
EUR 302.4

ZIP2 Antibody

ABF9234 100 ug
EUR 525.6

ZIP2 Antibody

AF9234 100ul
EUR 280
Description: Human

ZIP7 Antibody

AF6866 100ul
EUR 280
Description: Human,Mouse,Rat

ZIP7 Antibody

DF4635 100ul
EUR 280
Description: Human,Mouse,Rat

ZIP1 Antibody

CSB-PA339148XA11SVG 100ul / 50ul
EUR 299
Description: Synaptonemal complex protein ZIP1, ZIP1

ZIP1 Antibody

CAC11685-100ul 100ul
EUR 314

ZIP1 Antibody

CAC11685-50ul 50ul
EUR 199.2

ZIP1 Antibody

E047986 100μg/100μl
EUR 255
Description: Available in various conjugation types.

ZIP1 Antibody

E38PA5654 100ul
EUR 225
Description: Available in various conjugation types.

ZIP7 Antibody

E38PA2256 100ul
EUR 225
Description: Available in various conjugation types.

ZIP7 Antibody

AF6866-100ul 100ul
EUR 280

ZIP7 Antibody

AF6866-200ul 200ul
EUR 350

ZIP2 Antibody

AF9234-100ul 100ul
EUR 280

ZIP2 Antibody

AF9234-200ul 200ul
EUR 350

ZIP2 Antibody

E18-9234-1 50ug/50ul
EUR 145
Description: Available in various conjugation types.

ZIP2 Antibody

E18-9234-2 100ug/100ul
EUR 225
Description: Available in various conjugation types.

ZIP7 Antibody

DF4635-100ul 100ul
EUR 280

ZIP7 Antibody

DF4635-200ul 200ul
EUR 350

Zinc transporter ZIP13 Antibody (HRP)

20-abx109241
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

OAPB00823-100UG - ZIP11 Antibody

OAPB00823-100UG 0.1mg
EUR 389

NASBA has qualities that should be advantageous for analysis of environmental samples, such as short reaction times, high sensitivity, and not readily affected by inhibitory substances that are often abundant in environmental samples. NASBA is well suited for incorporation into lab-on-a-chip (LOC) devices, as part of analysis systems that can be taken into the field for on-site screening. In this review, we explore advantages and drawbacks of NASBA as a tool for environmental analyses, and try to answer the question of whether it will be a recognised technique in the same manner as in clinical diagnostics.

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